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Duan, Lei

One or more keywords matched the following items that are connected to Duan, Lei

Item Type	Name
Concept	Oncogene Protein v-cbl
Concept	Proto-Oncogene Proteins c-bcl-2
Concept	Oncogene Proteins
Concept	Proto-Oncogene Proteins c-cbl
Concept	Proto-Oncogene Proteins c-mdm2
Concept	Proto-Oncogene Proteins
Concept	Proto-Oncogene Proteins c-akt
Concept	Proto-Oncogene Proteins c-vav
Academic Article	Cbl-mediated ubiquitinylation is required for lysosomal sorting of epidermal growth factor receptor but is dispensable for endocytosis.
Academic Article	Cbl-mediated ubiquitinylation and negative regulation of Vav.
Academic Article	The Cbl family and other ubiquitin ligases: destructive forces in control of antigen receptor signaling.
Academic Article	A critical role for the E3-ligase activity of c-Cbl in VEGFR-2-mediated PLCgamma1 activation and angiogenesis.
Academic Article	Binding of Cbl to a phospholipase Cgamma1-docking site on platelet-derived growth factor receptor beta provides a dual mechanism of negative regulation.
Academic Article	Distinct roles for Rho versus Rac/Cdc42 GTPases downstream of Vav2 in regulating mammary epithelial acinar architecture.
Academic Article	Negative regulation of EGFR-Vav2 signaling axis by Cbl ubiquitin ligase controls EGF receptor-mediated epithelial cell adherens junction dynamics and cell migration.
Academic Article	The prolyl peptidases PRCP/PREP regulate IRS-1 stability critical for rapamycin-induced feedback activation of PI3K and AKT.
Academic Article	Increasing cisplatin sensitivity by schedule-dependent inhibition of AKT and Chk1.
Academic Article	p53-regulated autophagy is controlled by glycolysis and determines cell fate.
Academic Article	Modeling the Etiology of p53-mutated Cancer Cells.
Academic Article	Crosstalk between the IGF-1R/AKT/mTORC1 pathway and the tumor suppressors p53 and p27 determines cisplatin sensitivity and limits the effectiveness of an IGF-1R pathway inhibitor.
Academic Article	The IGF-1R/AKT pathway has opposing effects on Nutlin-3a-induced apoptosis.
Academic Article	p53 promotes AKT and SP1-dependent metabolism through the pentose phosphate pathway that inhibits apoptosis in response to Nutlin-3a.
Academic Article	DZNep represses Bcl-2 expression and modulates apoptosis sensitivity in response to Nutlin-3a.
Academic Article	The histone demethylase JMJD2B is critical for p53-mediated autophagy and survival in Nutlin-treated cancer cells.
Academic Article	Prolyl endopeptidase inhibitor Y-29794 blocks the IRS1-AKT-mTORC1 pathway and inhibits survival and in vivo tumor growth of triple-negative breast cancer.
Academic Article	Fatty acid oxidation and autophagy promote endoxifen resistance and counter the effect of AKT inhibition in ER-positive breast cancer cells.
Academic Article	Mixed lineage kinase 3 and CD70 cooperation sensitize trastuzumab-resistant HER2+ breast cancer by ceramide-loaded nanoparticles.

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Oncogene Proteins